Visual analysis of coronavirus disease 2019 (COVID-19) studies based on bibliometrics / 中国中药杂志

To analyze the development of coronavirus disease 2019(COVID-19), this study systematically retrieved relevant Chinese and English literatures from both CNKI and Web of Science database platforms by bibliometric research method and CiteSpace 5.5.R2 software to obtain information and visualize relevant literatures. A total of 695 Chinese and 446 English literatures were included in this paper. Statistics showed that China had published most of the literatures and established close cooperation with the United States and the United Kingdom. Through the analysis, Tongji Medical College of Huazhong University of Science and Technology and its affiliated hospitals published the largest number of the publications. Moreover, the highly productive journals including Journal of Traditional Chinese Medicine and The Lancet covered eight major fields, such as medicine, medical virology, radiation medicine, infectious disease, and traditional Chinese medicine. Besides, a total of 35 special COVID-19 funds were recently established to subsidize these studies. The key words and themes analysis indicated that protein structure of COVID-19, receptor targets and mechanisms of action, integration of traditional Chinese and Western medicine, screening and development of antiviral drugs from traditional Chinese medicine and Western medicine, vaccine research as well as epidemiological characteristics and prediction are current study hotspots. This study provides a reference for researchers to rapidly master main study directions of COVID-19 and screen out relevant literatures.

Development of whole process quality control and management system of traditional Chinese medicine decoction pieces based on traditional Chinese medicine quality tree / 中国中药杂志

The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization.

Effect of nitrogen supply on biomass accumulating and root respiration dynamic changing of Glycyrrhiza uralensis / 中国中药杂志

This paper aimed to study the effect nitrogen supplying on biomass accumulation and root respiration dynamic change of Glycyrrhiza uralensis and reveal the metabolic pathway of root respiration impact the biomass accumulating of G. uralensis. Six groups of one-year-old G. uralensis were fertilized with total nutrition containing various nitrogen concentration (0, 0.5, 1, 2, 4, 8 mmol x L(-1)) every week. At the end of every month, from June to October, the volume respiration rate and biomass of different classes of root samples were determined, and the correlation between root respiration and biomass was analyzed. The results indicated a negative correlation between volume respiration rate and biomass, nitrogen supply significantly affected both root respiration and biomass of G. uralensis by reducing root respiration and increasing root biomass. Under 8 mmol x L(-1) nitrogen supplying, there existed the optimal inhibition of root respiration, which has increased biomass of G. uralensis.

Research and investigation in medicine of Baima Tibetan in Pingwu Sichuan / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate and collect medicinal resources and methods of prevention and treatment of diseases in Baima Tibetan of Pingwu Sichuan in order to rescue and protect the ethenological medicine.</p><p><b>METHOD</b>Through visiting, field survey in four ethnic townships of Baima Tibetan in Pingwu Sichuan as well as referring literatures to collect information and data analysis of them the investigation was carried out.</p><p><b>RESULT</b>The investigation area showed rich medical resources. Rheumatism, stomach disease, pharyngitis and trauma are local common diseases which caused by local climate, diet and life style and so on. The Baima Tibetan are good at using local herb singly and simply to treat disease, using cold water medicine and powder snuffing are their own characters.</p><p><b>CONCLUSION</b>It is an extremely urgent issue to rescue Baima Tibetan medicine which is disappearing by the influence of the Han nationality culture.</p>

Effect of aqueous extracts on seed germination and seedling growth between Glycyrrhiza uralensis and Caragana microphylla / 中国中药杂志

<p><b>OBJECTIVE</b>To study the interspecies allelopathy of Glycyrrhiza uralensis and Caragana microphylla and reveal the relationship between different interactions and provided the theory reference for their application of compounding planting pattern in practice.</p><p><b>METHOD</b>Water extracts of G. uralensis and C. microphylla root, stem and leaf were used to dispose mutual seeds, young seedlings and transplants.</p><p><b>RESULT</b>The germination of G. uralensis seed wasn't restrained significantly by the water extract of C. microphylla root, stem and leaf (1-50 g x L(-1)). However, the inhibitory effect of a high concentration water extract of C. microphylla stem and leaf (50 g x L(-1) was stronger. There wasnt significant difference in the effect of the water extract of C. microphylla cast, root and stem on the growth and quality of G. uralensis transplant. Moreover, the water extract of G. uralensis root, stem and leaf can improve the germination of C. microphylla seeds and the growth of seedlings, while its effective extent didn't reach an obvious different level.</p><p><b>CONCLUSION</b>There exists no significant difference between the interspecies allelopathy of G. uralensis and C. microphylla.</p>

Effects of density on seedling growth and glycyrrhizinic acid content in Glycyrrhiza uralensis / 中国中药杂志

<p><b>OBJECTIVE</b>To study the principle of interaction among individuals and populations in different Glycyrrhiza uralensis growth density.</p><p><b>METHOD</b>The phenological characteristics, growth status, accumulation and distribution of biomass and glycyrrhizinic acid content of G. uralensis in different growth density were studied.</p><p><b>RESULT</b>Density had effect on phenological characteristics and growth status of G. uralensis seedling. The fast growing period of plant was advanced with the increase of the density, while the duration of fast growing period was decreased. Individual biomass decreased with the increase of the density, while population biomass increased. Biomass proportion of root, stem and leaf in individual were 65.02%, 19.55% and 15.43% respectively. Their relative standard deviations were 0.57, 0.49 and 0.76 respectively. Glycyrrhizinic acid content was 0.52% -0.59% under low density and 0.29% under high density.</p><p><b>CONCLUSION</b>The result showed that the density G. uralensis had a negative correlation with the shooting time of offshoot and underground stem, leaflet number, growth of plant height and diameter at ground, root head diameter, lateral root number, individual root and branch-leaf number, individual biomass and glycyrrhizinic acid content and a positive correlation with the population biomass.</p>

The underground part growth distribution pattern of Glycyrrhiza uralensis and its effects on glycyrrhizinic acid content / 中国中药杂志

<p><b>OBJECTIVE</b>To ascertain the relationship between glycyrrhizinic acid content and the underground part growth character of Glycyrrhiza uralensis and provide the theoretical evidence for wild resources protection and artificial cultivation method of G. uralensis.</p><p><b>METHOD</b>Through the analytical investigation on the underground part of G. uralensis and analysis of glycyrrhizinic acid content in different organs, parts, ages, and diameter medicinal materials, the systematic study on the relationship between glycyrrhizinic acid content and the underground part growth character of glycyrrhiza uralensis was carried out.</p><p><b>RESULT</b>The underground part of a G. uralensis seedling consisted of seed root, random root, horizontal underground stem, vertical underground stem and assimilating root. The glycyrrhizinic acid content in horizontal underground stem with the age below two years old or in random root with the diameter below 0.5 cm was low. The difference of glycyrrhizinic acid content among horizontal underground stem, random root and vertical underground stem was obvious, but the difference between horizontal underground stem and random root was not obvious.</p><p><b>CONCLUSION</b>The horizontal underground stem was of G. uralnesis acts as a link that can connect random root, vertical underground and stem assimilating root, so that the whole underground part constructs one huge underground net system. The glycyrrhizinic acid accumulation is a effected by organ type, growth age, root diameter and grow position, and the distribution pattern of random root and vertical underground stem has influence on glycyrrhizinic acid distribution in horizontal underground stem.</p>